Endocrine Abstracts

Introduction: This study aims to assess the performance of ultrasound using Kwak-TIRADS as the primary diagnostic tool for estimating papillary thyroid carcinoma (PTC) risk in thyroid nodules within the high-prevalence region of Crete, Greece.Methods: A retrospective analysis was conducted on 802 thyroid nodules collected between 2018 and 2021. Nodules were categorized based on Kwak-TIRADS and compared against the Bethesda System for Reporting Thyroid Cy...

Background: Carpal tunnel syndrome (CTS) is common in patients with acromegaly, with a reported prevalence of 19–64%. We have studied CTS in a large national cohort of patients with acromegaly, and the temporal relationship between the diagnosis of the two diseases.Methods: Retrospective nationwide cohort study including patients diagnosed with acromegaly in Sweden between 2005 and 2017. Patients with acromegaly were identified in the Swedish Natio...

Purpose: We aimed to validate the diagnosis and estimated national incidence of acromegaly reported in the Swedish National Patient Register (NPR), based on clinically reported International Classification of Diseases (ICD-codes), in comparison with the Swedish Pituitary Register (SPR).Methods: All patients in NPR or SPR between 1991-2018 with the ICD-9 or ICD-10 diagnosis of acromegaly and age >18 years at diagnosis were included. The diagnosis was ...

Introduction: Patients with acromegaly have an increased mortality, mainly due to cardiovascular and respiratory diseases. Sleep apnea is related to hypertension, stroke and cardiovascular diseases and is reported to occur in 11–30% of acromegaly patients, according to retrospective studies based on diagnostic ICD-codes. However, in smaller prospective studies sleep apnea is found in about 70% of patients with active acromegaly and 40% after biochemical control. This diff...

Background: Due to the rarity and the slow progress of the disease, there is a considerable diagnostic delay in acromegaly, contributing to increased morbidity and mortality. Voice analysis may decrease this delay as patients with acromegaly often develop a dark voice and unclear speech due to macroglossia, enlarged lips and edema in the pharynx and larynx. Modern technology offers higher speed and power of voice analysis and increased the interest in voice as a biomarker to i...